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Like Methionine, obesity and insulin resistance are thought to be strong activators of mTOR
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A 2025 European Journal of Clinical Nutrition commentary on the NICE guideline argued that the diagnostic threshold and clinical awareness still need to be tightened further, especially around pernicious anaemia, which is still under-recognised in primary care
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This adds 30 seconds to the reconstitution workflow and eliminates the "wait, when did I open this?" question that's the most-cited cause of accidentally running past 28 days
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